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Neonatal Ebola infection: An Interesting Issue in Pediatric Infectious Disease

AUTHORS

Viroj Wiwanitkit 1 , *

1 Faculty of Medicine, University of Nis, Serbia, Chulalongkorn University, Bangkok, Thailand

How to Cite: Wiwanitkit V. Neonatal Ebola infection: An Interesting Issue in Pediatric Infectious Disease, Arch Pediatr Infect Dis. 2016 ; 4(3):e36211. doi: 10.5812/pedinfect.36211.

ARTICLE INFORMATION

Archives of Pediatric Infectious Diseases: 4 (3); e36211
Published Online: May 9, 2016
Article Type: Letter
Received: January 10, 2016
Revised: March 12, 2016
Accepted: April 11, 2016
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Keywords

Ebola Infection Newborn

Copyright © 2016, Pediartric Infections Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Dear Editor,

Ebola virus infection is a current global concern (1). This infection caused several deaths in Africa in 2015 (1). Ebola virus infection can occur in any age group. In pediatrics, the mortality rate of Ebola is very high (2). Neonatal Ebola infection is a particular area of interest. The first issue to be discussed is transplacental transmission and congenital Ebola infection in newborns. Infection in pregnant women can affect newborns (3, 4). In the current outbreak, Oduyebo et al. recently reported a case of Ebola in a mother infected in her third trimester who delivered a stillborn fetus (5). A previous report from Congo also recounted a case of a stillborn fetus (6). It seems that the infection is very virulent, and the affected fetus does not usually survive. Nevertheless, Ebola infection among the newborns has been observed. According to the report from Congo by Formenty et al., the youngest case was a five-day-old newborn, and there is high mortality among newborns even when the clinical presentation is only a fever (7). In Uganda, a case was reported in a three day old. A similar, very high fatality rate among newborns was also observed (8). The possibility of perinatal infection can be seen in these cases from Congo and Uganda where there was no evidence of Ebola infection in the mother during pregnancy (7, 8). Intrafamilial transmission from other members of the family to the neonates via body fluid contact is proposed (7, 8). In a recent publication in Am J Infect Control, the transmission of Ebola to a newborn through contact with the mother’s body fluid was reported (9). In conclusion, as seen in clinical practice, neonatal Ebola virus infection has a very high mortality rate. Practitioners should be made aware of this risk.

References

  • 1.

    Wiwanitkit V. Ebola virus infection: what should be known? N Am J Med Sci. 2014; 6(11) : 549 -52 [DOI][PubMed]

  • 2.

    W. H. O. Ebola Response Team , Agua-Agum J, Ariyarajah A, Blake IM, Cori A, Donnelly CA, et al. Ebola virus disease among children in West Africa. N Engl J Med. 2015; 372(13) : 1274 -7 [DOI][PubMed]

  • 3.

    Black BO, Caluwaerts S, Achar J. Ebola viral disease and pregnancy. Obstet Med. 2015; 8(3) : 108 -13 [DOI][PubMed]

  • 4.

    Ebola: caring for pregnant and postpartum women and newborns in the United States: AWHONN practice brief number 3. J Obstet Gynecol Neonatal Nurs. 2015; 44(1) : 164 -5 [DOI][PubMed]

  • 5.

    Oduyebo T, Pineda D, Lamin M, Leung A, Corbett C, Jamieson DJ. A Pregnant Patient With Ebola Virus Disease. Obstet Gynecol. 2015; 126(6) : 1273 -5 [DOI][PubMed]

  • 6.

    Mupapa K, Mukundu W, Bwaka MA, Kipasa M, De Roo A, Kuvula K, et al. Ebola hemorrhagic fever and pregnancy. J Infect Dis. 1999; 179 Suppl 1 -2 [DOI][PubMed]

  • 7.

    Formenty P, Libama F, Epelboin A, Allarangar Y, Leroy E, Moudzeo H, et al. [Outbreak of Ebola hemorrhagic fever in the Republic of the Congo, 2003: a new strategy?]. Med Trop (Mars). 2003; 63(3) : 291 -5 [PubMed]

  • 8.

    Mupere E, Kaducu OF, Yoti Z. Ebola haemorrhagic fever among hospitalised children and adolescents in northern Uganda: epidemiologic and clinical observations. Afr Health Sci. 2001; 1(2) : 60 -5 [PubMed]

  • 9.

    Dunn AC, Walker TA, Redd J, Sugerman D, McFadden J, Singh T, et al. Nosocomial transmission of Ebola virus disease on pediatric and maternity wards: Bombali and Tonkolili, Sierra Leone, 2014. Am J Infect Control. 2016; 44(3) : 269 -72 [DOI][PubMed]

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