Archives of Pediatric Infectious Diseases

Published by: Kowsar

Diabetic Foot Infections: Antibiotic Susceptibility Patterns and Determination of Antibiotic Cross-Resistance in Clinical Isolates of Enterococcus Species During 2012 - 2014 in Shiraz, Iran

Mojtaba Anvarinejad 1 , Gholamreza Pouladfar 1 , Aziz Japoni 1 , Shahram Bolandparvaz 2 , Zeinab Satiary 3 and Jalal Mardaneh 4 , *
Authors Information
1 Prof. Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Head of Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 General Surgery Ward, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
4 Department of Microbiology, School of Medicine, Gonabad University of Medical Sciences, Gonabad, IR Iran
Article information
  • Archives of Pediatric Infectious Diseases: April 01, 2017, 5 (2); e37680
  • Published Online: September 6, 2016
  • Article Type: Research Article
  • Received: March 7, 2016
  • Revised: August 3, 2016
  • Accepted: August 20, 2016
  • DOI: 10.5812/pedinfect.37680

To Cite: Anvarinejad M, Pouladfar G, Japoni A, Bolandparvaz S, Satiary Z, et al. Diabetic Foot Infections: Antibiotic Susceptibility Patterns and Determination of Antibiotic Cross-Resistance in Clinical Isolates of Enterococcus Species During 2012 - 2014 in Shiraz, Iran, Arch Pediatr Infect Dis. 2017 ; 5(2):e37680. doi: 10.5812/pedinfect.37680.

Copyright © 2016, Pediartric Infections Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Lipsky BA, Richard JL, Lavigne JP. Diabetic foot ulcer microbiome: one small step for molecular microbiology . . . One giant leap for understanding diabetic foot ulcers? Diabetes. 2013; 62(3): 679-81[DOI][PubMed]
  • 2. Dowd SE, Wolcott RD, Sun Y, McKeehan T, Smith E, Rhoads D. Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP). PLoS One. 2008; 3(10): 3326[DOI][PubMed]
  • 3. Lipsky BA. Empirical therapy for diabetic foot infections: are there clinical clues to guide antibiotic selection? Clin Microbiol Infect. 2007; 13(4): 351-3[DOI][PubMed]
  • 4. Ismail K, Winkley K, Stahl D, Chalder T, Edmonds M. A cohort study of people with diabetes and their first foot ulcer: the role of depression on mortality. Diabetes Care. 2007; 30(6): 1473-9[DOI][PubMed]
  • 5. Semedo-Lemsaddek T, Mottola C, Alves-Barroco C, Cavaco-Silva P, Tavares L, Oliveira M. Characterization of multidrug-resistant diabetic foot ulcer enterococci. Enferm Infecc Microbiol Clin. 2016; 34(2): 114-6[DOI][PubMed]
  • 6. Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJ, Armstrong DG, et al. 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2012; 54(12): 132-73[DOI][PubMed]
  • 7. Anvarinejad M, Pouladfar G, Japoni A, Bolandparvaz S, Satiary Z, Abbasi P, et al. Isolation and Antibiotic Susceptibility of the Microorganisms Isolated from Diabetic Foot Infections in Nemazee Hospital, Southern Iran. J Pathog. 2015; 2015: 328796[DOI][PubMed]
  • 8. Ki V, Rotstein C. Bacterial skin and soft tissue infections in adults: A review of their epidemiology, pathogenesis, diagnosis, treatment and site of care. Can J Infect Dis Med Microbiol. 2008; 19(2): 173-84[PubMed]
  • 9. Peters EJ, Lipsky BA, Aragon-Sanchez J, Boyko EJ, Diggle M, Embil JM, et al. Interventions in the management of infection in the foot in diabetes: a systematic review. Diabetes Metab Res Rev. 2016; 32 Suppl 1: 145-53[DOI][PubMed]
  • 10. Bondor CI, Veresiu IA, Florea B, Vinik EJ, Vinik AI, Gavan NA. Epidemiology of Diabetic Foot Ulcers and Amputations in Romania: Results of a Cross-Sectional Quality of Life Questionnaire Based Survey. J Diabetes Res. 2016; 2016: 5439521[DOI][PubMed]
  • 11. Clinical and Laboratory Standards Institute. 2011; 31
  • 12. Tiwari S, Pratyush DD, Dwivedi A, Gupta SK, Rai M, Singh SK. Microbiological and clinical characteristics of diabetic foot infections in northern India. J Infect Dev Ctries. 2012; 6(4): 329-32[PubMed]
  • 13. Grayson ML. Diabetic foot infections. Antimicrobial therapy. Infect Dis Clin North Am. 1995; 9(1): 143-61[PubMed]
  • 14. Senneville E, Yazdanpanah Y, Cazaubiel M, Cordonnier M, Valette M, Beltrand E, et al. Rifampicin-ofloxacin oral regimen for the treatment of mild to moderate diabetic foot osteomyelitis. J Antimicrob Chemother. 2001; 48(6): 927-30[PubMed]
  • 15. El-Tahawy AT. Bacteriology of diabetic foot. Saudi Med J. 2000; 21(4): 344-7[PubMed]
  • 16. Shaghaghian S, Pourabbas B, Alborzi A, Askarian M, Mardaneh J. Vancomycin-Resistant Entrococci colonization in chronic hemodialysis patients and its risk factors in southern Iran (2005-2006). Iran Red Crescent Med J. 2012; 14(10): 686-91[PubMed]
  • 17. Anvarinejad M, Japoni A, Rafaatpour N, Mardaneh J, Abbasi P, Amin Shahidi M, et al. Burn Patients Infected With Metallo-Beta-Lactamase-Producing Pseudomonas aeruginosa: Multidrug-Resistant Strains. Arch Trauma Res. 2014; 3(2): 18182[DOI][PubMed]
  • 18. Citron DM, Goldstein EJ, Merriam CV, Lipsky BA, Abramson MA. Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents. J Clin Microbiol. 2007; 45(9): 2819-28[DOI][PubMed]
  • 19. Karakus A, Ozkan M, Karcioglu M, Ozden R, Ustun I, Caliskan K, et al. Diabetic foot due to anaphylactic shock: a case report. Arch Trauma Res. 2014; 3(2): 17610[DOI][PubMed]
  • 20. Poorabbas B, Mardaneh J, Rezaei Z, Kalani M, Pouladfar G, Alami MH, et al. Nosocomial Infections: Multicenter surveillance of antimicrobial resistance profile of Staphylococcus aureus and Gram negative rods isolated from blood and other sterile body fluids in Iran. Iran J Microbiol. 2015; 7(3): 127-35[PubMed]
  • 21. Goldstein EJ, Citron DM, Nesbit CA. Diabetic foot infections. Bacteriology and activity of 10 oral antimicrobial agents against bacteria isolated from consecutive cases. Diabetes Care. 1996; 19(6): 638-41[PubMed]
  • 22. Mardaneh J, Soltan-Dallal MM. Isolation and Identification of E. cowanii from Powdered Infant Formula in NICU and Determination of Antimicrobial Susceptibility of Isolates. Iran J Pediatr. 2014; 24(3): 261-6[PubMed]
  • 23. Soltani J, Poorabbas B, Miri N, Mardaneh J. Health care associated infections, antibiotic resistance and clinical outcome: A surveillance study from Sanandaj, Iran. World J Clin Cases. 2016; 4(3): 63-70[DOI][PubMed]
  • 24. Anvarinejad M, Pouladfar GR, Pourabbas B, Amin Shahidi M, Rafaatpour N, Dehyadegari MA, et al. Detection of Salmonella spp. with the BACTEC 9240 Automated Blood Culture System in 2008 - 2014 in Southern Iran (Shiraz): Biogrouping, MIC, and Antimicrobial Susceptibility Profiles of Isolates. Jundishapur J Microbiol. 2016; 9(4): 26505[DOI][PubMed]
  • 25. Mardaneh J, Soltan Dallal MM. Isolation and Identification Enterobacter asburiae from Consumed Powdered Infant Formula Milk (PIF) in the Neonatal Intensive Care Unit (NICU). Acta Med Iran. 2016; 54(1): 39-43[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments