Archives of Pediatric Infectious Diseases

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Successful Treatment of Splenomegaly and Pancytopenia with Rituximab in a Patient with Nijmegen Breakage Syndrome

Hoshang Gorjipour 1 , Golnaz Eslamyan 2 , Mehrnaz Mesdaghi 1 , * , Mahboubeh Mansouri 1 , Abdollah Karimi 3 , Payman Eshghi 4 , Delara Babaie 1 , Mehrdad Amirmoeni 1 , Bahram Bashardust 1 , Marjan Shakiba 5 and Zahra Chavoshzadeh 1
Authors Information
1 Department of Allergy and Immunology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Pediatrics, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Pediatric Infections Research Center, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Department of Pediatric Hematology and Oncology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5 Department of Endocrinology and Metabolism, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Article information
  • Archives of Pediatric Infectious Diseases: April 01, 2017, 5 (2); e37026
  • Published Online: October 18, 2016
  • Article Type: Case Report
  • Received: March 1, 2016
  • Revised: September 5, 2016
  • Accepted: October 1, 2016
  • DOI: 10.5812/pedinfect.37026

To Cite: Gorjipour H, Eslamyan G, Mesdaghi M, Mansouri M, Karimi A, et al. Successful Treatment of Splenomegaly and Pancytopenia with Rituximab in a Patient with Nijmegen Breakage Syndrome, Arch Pediatr Infect Dis. 2017 ; 5(2):e37026. doi: 10.5812/pedinfect.37026.

Abstract
Copyright © 2016, Pediartric Infections Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
References
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  • 2. Wegner R, Chrzanowska K, Sperling K, Stumm M. Ataxia-telangiectasia variants (Nijmegen breakage syndrome). 1999;
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  • 7. Levy J, Espanol-Boren T, Thomas C, Fischer A, Tovo P, Bordigoni P. Clinical spectrum of X-linked hyper-IgM syndrome. Pediat J. 1997; 131(1): 47-54[DOI][PubMed]
  • 8. Hennig C, Baumann U, Ilginus C, Horneff G, Foell J, Hansen G, et al. Successful treatment of autoimmune and lymphoproliferative complications of patients with intrinsic B-cell immunodeficiencies with Rituximab. Br J Haematol. 2010; 148(3): 445-8
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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