Archives of Pediatric Infectious Diseases

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Correlation Between hlyA and cnf1 Virulent Genes with Antibiotic Resistance and non-ESBLs Escherichia coli Isolates Collected from Patient with Urinary Tract Infections in Kerman, Iran

Zahra Hashemizadeh 1 , Davood Kalantar-Neyestanaki 1 , 2 and Shahla Mansouri 1 , 3 , *
Authors Information
1 Department of Microbiology and Virology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
2 Student Research Committee, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
3 Research Center for Infectious Diseases and Tropical Medicine, Kerman, Iran
Article information
  • Archives of Pediatric Infectious Diseases: October 2017, 5 (4); e61653
  • Published Online: September 27, 2017
  • Article Type: Research Article
  • Received: July 6, 2016
  • Revised: October 4, 2016
  • Accepted: October 28, 2016
  • DOI: 10.5812/pedinfect.61653

To Cite: Hashemizadeh Z, Kalantar-Neyestanaki D, Mansouri S. Correlation Between hlyA and cnf1 Virulent Genes with Antibiotic Resistance and non-ESBLs Escherichia coli Isolates Collected from Patient with Urinary Tract Infections in Kerman, Iran, Arch Pediatr Infect Dis. 2017 ; 5(4):e61653. doi: 10.5812/pedinfect.61653.

Copyright © 2017, Archives of Pediatric Infectious Diseases. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Birosova E, Siegfried L, Kmet'ova M, Makara A, Ostro A, Gresova A, et al. Detection of virulence factors in alpha-haemolytic Escherichia coli strains isolated from various clinical materials. Clin Microbiol Infect. 2004; 10(6): 569-73[DOI][PubMed]
  • 2. Navidinia M, Najar Peerayeh S, Fallah F, Bakhshi B. Phylogenetic groups and pathogenicity island markers in Escherichia coli isolated from children. Jundishapur J Microbiol. 2013; 6(10)[DOI]
  • 3. Sobieszczanska BM, Osek J, Gryko R, Dobrowolska M. Association between cell-bound haemolysin and cell-detaching activity of Escherichia coli isolated from children. J Med Microbiol. 2006; 55: 325-30[DOI][PubMed]
  • 4. Harwalkar A, Gupta S, Rao A, Srinivasa H. Lower prevalence of hlyD, papC and cnf-1 genes in ciprofloxacin-resistant uropathogenic Escherichia coli than their susceptible counterparts isolated from souther India. J Infect Public Health. 2014; 7(5): 413-9[DOI][PubMed]
  • 5. Soltani J, Poorabbas B, Miri N, Mardaneh J. Health care associated infections, antibiotic resistance and clinical outcome: A surveillance study from Sanandaj, Iran. World J Clin Cases. 2016; 4(3): 63-70[DOI][PubMed]
  • 6. Tabasi M, Asadi Karam MR, Habibi M, Yekaninejad MS, Bouzari S. Phenotypic Assays to Determine Virulence Factors of Uropathogenic Escherichia coli (UPEC) Isolates and their Correlation with Antibiotic Resistance Pattern. Osong Public Health Res Perspect. 2015; 6(4): 261-8[DOI][PubMed]
  • 7. Martin WJ, Washington II JA. Manual of clinical microbiology. 1980; : 195-219
  • 8. Clinical and Laboratory Standards Institute . Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement. M100-S24. 2015; 34(1): 44-50
  • 9. Pitout JD, Gregson DB, Poirel L, McClure JA, Le P, Church DL. Detection of Pseudomonas aeruginosa producing metallo-beta-lactamases in a large centralized laboratory. J Clin Microbiol. 2005; 43(7): 3129-35[DOI][PubMed]
  • 10. Blanco M, Blanco JE, Rodrı́guez E, Abalia I, Alonso MP, Blanco J. Detection of virulence genes in uropathogenic Escherichia coli by polymerase chain reaction (PCR): comparison with results obtained using phenotypic methods. J Microbiol Methods. 1997; 31(1-2): 37-43[DOI]
  • 11. Yamamoto S, Terai A, Yuri K, Kurazono H, Takeda Y, Yoshida O. Detection of urovirulence factors in Escherichia coli by multiplex polymerase chain reaction. FEMS Immunol Med Microbiol. 1995; 12(2): 85-90[DOI][PubMed]
  • 12. Asadi S, Kargar M, Solhjoo K, Najafi A, Ghorbani-Dalini S. The association of virulence determinants of uropathogenic escherichia coli with antibiotic resistance. Jundishapur J Microbiol. 2014; 7(5)[DOI]
  • 13. Farshad S, Emamghorashi F. The prevalence of virulence genes of E. coli strains isolated from children with urinary tract infection. Saudi J Kidney Dis Transpl. 2009; 20(4): 613-7[PubMed]
  • 14. Abdi S, Ranjbar R, Hakemi Vala M, Jonaidi N, Baghery Bejestany O, Baghery Bejestany F. Frequency of bla TEM, bla SHV, bla CTX-M, and qnrA among escherichia coli isolated from urinary tract infection. Arch Clin Infect Dis. 2014; 9(1)[DOI]
  • 15. Riyahi Zaniani F, Meshkat Z, Naderi Nasab M, Khaje-Karamadini M, Ghazvini K, Rezaee A. The Prevalence of TEM and SHV Genes among Extended-Spectrum Beta-Lactamases Producing Escherichia coli and Klebsiella pneumoniae. Iran J Basic Med Sci. 2012; 15(1): 654-60
  • 16. Staji H, Khoshgoftar J, Javaheri Vayeghan A, Salimi Bejestani MR. Phylogenetic grouping and assessment of virulence genotypes, with antibiotic resistance patterns, of escherichia coli strains implicated in female urinary tract infections. Int J Enteric Pathog. 2016; 4(1)[DOI]
  • 17. Velasco M, Horcajada JP, Mensa J, Moreno-Martinez A, Vila J, Martinez JA, et al. Decreased invasive capacity of quinolone-resistant Escherichia coli in patients with urinary tract infections. Clin Infect Dis. 2001; 33(10): 1682-6[DOI][PubMed]
  • 18. Arisoy M, Rad AY, Akin A, Akar N. Relationship between susceptibility to antimicrobials and virulence factors in paediatric Escherichia coli isolates. Int J Antimicrob Agents. 2008; 31 Suppl 1-8[DOI][PubMed]
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