Archives of Pediatric Infectious Diseases

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The Relationship of Class I Integron Gene Cassettes and the Multidrug-Resistance in Extended -Spectrum β-Lactamase Producing Isolates of Escherichia coli

Alisha Akya 1 , Roya Chegene Lorestani 1 , Mosayeb Rostamian 1 , Azam Elahi 1 , Shokofe Baakhshii 2 , Minoo Aliabadi 1 and Keyghobad Ghadiri 1 , *
Authors Information
1 Infection Diseases Research Centre, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 Department of Biology, Faculty of Basic Sciences, Islamic Azad University of Boroujerd, Boroujerd, Iran
Article information
  • Archives of Pediatric Infectious Diseases: In Press (In Press); e87961
  • Published Online: July 6, 2019
  • Article Type: Research Article
  • Received: December 19, 2018
  • Revised: May 5, 2019
  • Accepted: May 13, 2019
  • DOI: 10.5812/pedinfect.87961

To Cite: Akya A, Chegene Lorestani R, Rostamian M, Elahi A, Baakhshii S, et al. The Relationship of Class I Integron Gene Cassettes and the Multidrug-Resistance in Extended -Spectrum β-Lactamase Producing Isolates of Escherichia coli, Arch Pediatr Infect Dis. Online ahead of Print ; In Press(In Press):e87961. doi: 10.5812/pedinfect.87961.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Footnotes
References
  • 1. Kumar S, Dave A, Wolf B, Lerma EV. Urinary tract infections. Dis Mon. 2015;61(2):45-59. doi: 10.1016/j.disamonth.2014.12.002. [PubMed: 25732782].
  • 2. Ranjbaran M, Zolfaghari M, Japoni-Nejad A, Amouzandeh-Nobaveh A, Abtahi H, Tabib Nejad M, et al. [Molecular Investigation of Integrons in Escherichia Coli and Klebsiella Pneumoniae Isolated from Urinary Tract Infections]. J Mazandaran Univ Med Sci. 2013;23(105):20-7. Persian.
  • 3. Haddadi A, Mikaili Ghezeljeh S, Shavandi M. Prevalence of class 1 and 2 integrons among the multidrug resistant uropathogenic strains of Escherichia coli. Asian Biomed. 2017;9(1):49-54. doi: 10.5372/1905-7415.0901.367.
  • 4. Zeighami H, Haghi F, Hajiahmadi F. [Integrons and their role in antibiotic resistance]. Zanjan Univ Med Sci. 2014;5(22):61-71. Persian.
  • 5. Kargar M, Mohammadalipour Z, Doosti A, Lorzadeh S, Japoni-Nejad A. High prevalence of class 1 to 3 integrons among multidrug-resistant diarrheagenic Escherichia coli in Southwest of Iran. Osong Public Health Res Perspect. 2014;5(4):193-8. doi: 10.1016/j.phrp.2014.06.003. [PubMed: 25379369]. [PubMed Central: PMC4215003].
  • 6. Domingues S, da Silva GJ, Nielsen KM. Integrons: Vehicles and pathways for horizontal dissemination in bacteria. Mob Genet Elements. 2012;2(5):211-23. doi: 10.4161/mge.22967. [PubMed: 23550063]. [PubMed Central: PMC3575428].
  • 7. Partridge SR, Tsafnat G, Coiera E, Iredell JR. Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiol Rev. 2009;33(4):757-84. doi: 10.1111/j.1574-6976.2009.00175.x. [PubMed: 19416365].
  • 8. Guo X, Xia R, Han N, Xu H. Genetic diversity analyses of class 1 integrons and their associated antimicrobial resistance genes in Enterobacteriaceae strains recovered from aquatic habitats in China. Lett Appl Microbiol. 2011;52(6):667-75. doi: 10.1111/j.1472-765X.2011.03059.x. [PubMed: 21496063].
  • 9. Mahluji Z, Firoozeh F, Khorshidi A, Zibaei M. [The frequency of class 1 integrons in multi-drug resistant Klebsiellapneumoniae isolated from clinical samples using polymerase chain reaction assay]. Sci J Kurdistan Univ Med Sci. 2016;21(3):68-78. Persian.
  • 10. Mehdipour Moghaddam MJ, Mirbagheri AA, Salehi Z, Habibzade SM. Prevalence of class 1 integrons and extended spectrum beta lactamases among multi-drug resistant Escherichia coli isolates from North of Iran. Iran Biomed J. 2015;19(4):233-9. [PubMed: 26220727]. [PubMed Central: PMC4649859].
  • 11. Ibrahim N, Wajidi MF, Yusof MY, Tay ST. The integron prevalence of extended-spectrum beta-lactamase producing enterobacterial isolates in a Malaysian teaching hospital. Trop Biomed. 2011;28(3):668-71. [PubMed: 22433898].
  • 12. Machado E, Canton R, Baquero F, Galan JC, Rollan A, Peixe L, et al. Integron content of extended-spectrum-beta-lactamase-producing Escherichia coli strains over 12 years in a single hospital in Madrid, Spain. Antimicrob Agents Chemother. 2005;49(5):1823-9. doi: 10.1128/AAC.49.5.1823-1829.2005. [PubMed: 15855502]. [PubMed Central: PMC1087637].
  • 13. Fauci S, Braunwald E, Kasper DL, Longo DL, Braunwald E, Hauser SL, et al. Harrison's principles of internal medicine. USA: McGraw-Hill; 2008.
  • 14. Washington C, Stephen A, Janda W, Koneman E, Procop G, Schreckenberger P. Koneman's color atlas and textbook of diagnostic microbiology. Lippincott: Williams & Wilkins; 2006.
  • 15. Wayne PA. CLSI informational supplement, performance standards for antimicrobial susceptibility testing. USA: Clinical and Laboratory Standards Institute; 2017.
  • 16. Ahangarzadeh Rezaee M, Langarizadeh N, Aghazadeh M. First report of class 1 and class 2 integrons in multidrug-resistant Klebsiella pneumoniae isolates from Northwest Iran. Japan J Infect Dis. 2012;65(3):256-9.
  • 17. Chegene Lorestani R, Akya A, Elahi A, Hamzavi Y. Gene cassettes of class I integron-associated with antimicrobial resistance in isolates of Citrobacter spp. with multidrug resistance. Iran J Microbiol. 2018;10(1):22.
  • 18. Mirnejad R, Mostofi S, Masjedian F. Antibiotic resistance and carriage class 1 and 2 integrons in clinical isolates of Acinetobacter baumannii from Tehran, Iran. Asian Pac J Trop Biomed. 2013;3(2):140-5. doi: 10.1016/S2221-1691(13)60038-6. [PubMed: 23593593]. [PubMed Central: PMC3627174].
  • 19. Khoramrooz SS, Sharifi A, Yazdanpanah M, Malek Hosseini SA, Emaneini M, Gharibpour F, et al. High frequency of class 1 integrons in Escherichia coli isolated from patients with urinary tract infections in Yasuj, Iran. Iran Red Crescent Med J. 2016;18(1). e26399. doi: 10.5812/ircmj.26399. [PubMed: 26889395]. [PubMed Central: PMC4752967].
  • 20. Eslami G, Seyedjavadi SS, Goudarzi H, Fallah F, Goudarzi M. [Distribution of integrons among multidrug resistant E. coli and Klebsiella strains]. Res Med. 2010;34(1):61-5. Persian.
  • 21. Adel El-Sokkary M, Abdelmegeed ES. Characterisation of class 1 integron among Escherichia coli isolated from Mansoura University Hospitals in Egypt. Adv Microbiol. 2015;5(4):269-77. doi: 10.4236/aim.2015.54025.
  • 22. Japoni-Nejad A, Gudarzi M, Farshad S, Basiri E, Ziyaeyan M, Alborzi A, et al. Assay for integrons and pattern of antibiotic resistance in clinical Escherichia coli strains by PCR-RFLP in Southern Iran. Japan J Infect Dis. 2008;61(1):85.
  • 23. Bhattacharjee A, Sen MR, Prakash P, Gaur A, Anupurba S, Nath G. Observation on integron carriage among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases. Indian J Med Microbiol. 2010;28(3):207-10. doi: 10.4103/0255-0857.66472. [PubMed: 20644307].
  • 24. Yao F, Qian Y, Chen S, Wang P, Huang Y. Incidence of extended-spectrum beta-lactamases and characterization of integrons in extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated in Shantou, China. Acta Biochim Biophys Sin (Shanghai). 2007;39(7):527-32. doi: 10.1111/j.1745-7270.2007.00304.x. [PubMed: 17622472].
  • 25. Abd El-Rahman S, Ismail Y, Fathy Alhusseini N, Abbas S. Role of integrons in multidrug resistant extended-spectrum β-lactamase producing enterobacteriaceae. J Microbiol Antimicrobials. 2014;6(7):104-10. doi: 10.5897/jma2014.0325.
  • 26. Zeighami H, Haghi F, Hajiahmadi F. Molecular characterization of integrons in clinical isolates of betalactamase-producing Escherichia coli and Klebsiella pneumoniae in Iran. J Chemother. 2015;27(3):145-51. doi: 10.1179/1973947814Y.0000000180. [PubMed: 24571248].
  • 27. Oliveira-Pinto C, Diamantino C, Oliveira PL, Reis MP, Costa PS, Paiva MC, et al. Occurrence and characterization of class 1 integrons in Escherichia coli from healthy individuals and those with urinary infection. J Med Microbiol. 2017;66(5):577-83. doi: 10.1099/jmm.0.000468. [PubMed: 28485709].
  • 28. Lima AM, de Melo ME, Alves LC, Brayner FA, Lopes AC. Investigation of class 1 integrons in Klebsiella pneumoniae clinical and microbiota isolates belonging to different phylogenetic groups in Recife, State of Pernambuco. Rev Soc Bras Med Trop. 2014;47(2):165-9. [PubMed: 24861289].
  • 29. Sung JY, Oh JE. Distribution and characterization of integrons in enterobacteriaceae isolates from chickens in Korea. J Microbiol Biotechnol. 2014;24(7):1008-13. [PubMed: 24851814].
  • 30. Yan H, Li L, Zong M, Alam MJ, Shinoda S, Shi L. Occurrence and characteristics of class 1 and 2 integrons in clinical bacterial isolates from patients in South China. J Health Sci. 2010;56(4):442-50. doi: 10.1248/jhs.56.442.
  • 31. Hajiahmadi F, Safari N, Alijani P, Rabiei M, Masomian N, Arabestani MR. Assessment of the prevalence of class i and ii integrons of Escherichia coli and klebsiella pneumoniae isolates from hospitals of Hamadan. Avicenna J Clin Med. 2016;23(3):193-201. doi: 10.21859/hums-23036.
  • 32. Masoumian N, Haghi F. [Analysis of integrons and associated gene cassettes in clinical isolates of Escherichia coli]. J Zanjan Univ Med Sci. 2015;23(99):74-82. Persian.
  • 33. Salimizand H, Shahcheraghi F, Kalantar E, Badmasti F, Mousavi SF. Molecular characterization of class 1 integrons and gene cassettes in multidrug resistant (MDR) Klebsiella spp. isolated from hospitalized and outpatients in Iran, 2009. Iran J Microbiol. 2013;5(1):48-55. [PubMed: 23466743]. [PubMed Central: PMC3577558].
  • 34. Chen J, Su Z, Liu Y, Wang S, Dai X, Li Y, et al. Identification and characterization of class 1 integrons among Pseudomonas aeruginosa isolates from patients in Zhenjiang, China. Int J Infect Dis. 2009;13(6):717-21. doi: 10.1016/j.ijid.2008.11.014. [PubMed: 19208492].
  • 35. Chen X, Li GX, Zhang H, Yuan M, Hou XP, Yu HL, et al. Characterization of class 1 integron gene cassettes among clinical bacteria isolated from one large hospital in northern China. Biomed Environ Sci. 2013;26(12):1003-7. doi: 10.3967/bes2013.038. [PubMed: 24393512].
  • 36. Ammar AM, Attia AM, Abd El-Aziz NK, Abd El Hamid MI, El-Demerdash AS. Class 1 integron and associated gene cassettes mediating multiple-drug resistance in some food borne pathogens. Int Food Res J. 2016;23(1):332-9.

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